Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Oct 21, 2022

Coronaviruses use a broad range of host receptors for binding and cell entry, essential steps in establishing viral infections. This pilot study evaluated the overall distribution of angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and dipeptidyl peptidase 4 (DPP4) receptors in the pig respiratory and intestinal tract. All the receptors evaluated in this study were expressed and differentially distributed through the respiratory and intestinal tract. The presence and expression levels of these receptors could determine susceptibility to coronavirus infections. This study may have important implications for the development of research models and the assessment of the potential risk and introduction of novel coronaviruses into the swine population.

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Video: WARNING! Rough Start To Breeding Season!!

WARNING! Sheep Breeding Season Begins With A Bang! Breeding season is officially underway at Ewetopia Farms, but it didn’t exactly start the way we planned!

This vlog begins with us sorting through our rams to find the perfect match for a customer’s breeding program. What should have been routine quickly turned dangerous when one of our more nervous rams panicked. In seconds, Arnie’s knee was injured, and then I was slammed hard onto the concrete floor — both of us taken down by one ram!

Thankfully, it was just bruises, but it’s a reminder of how unpredictable and powerful mature rams can be. Once we recovered, it was time to get back to the real work — the start of breeding season.

We sorted the ewes into four breeding groups (two Suffolk and two Dorset), checking parentage as they ran through the chute, deworming those that needed it, and setting aside thinner ewes for session two of breeding season in a month’s time.This staggered approach keeps lambing organized and prevents overcrowding in the barns.

From rogue rams to the excitement of new breeding groups, this episode is full of action. Stay tuned for the next vlog, where we’ll share how we chose the rams for each group!