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Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Coronaviruses use a broad range of host receptors for binding and cell entry, essential steps in establishing viral infections. This pilot study evaluated the overall distribution of angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and dipeptidyl peptidase 4 (DPP4) receptors in the pig respiratory and intestinal tract. All the receptors evaluated in this study were expressed and differentially distributed through the respiratory and intestinal tract. The presence and expression levels of these receptors could determine susceptibility to coronavirus infections. This study may have important implications for the development of research models and the assessment of the potential risk and introduction of novel coronaviruses into the swine population.

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Inside the National Swine Health Strategy - Dr. Dustin Oedekoven

Video: Inside the National Swine Health Strategy - Dr. Dustin Oedekoven



In this episode of The Swine it Podcast Show, Dr. Dustin Oedekoven, Chief Veterinarian at the National Pork Board, explains the producer-led National Swine Health Strategy and why it is essential for improving U.S. swine health. He discussed industry collaboration, the strategy's initial priorities, why PEDV is the first focus for elimination, research initiatives, and the long-term vision for healthier herds. Listen now on all major platforms.

"The National Swine Health Strategy creates a coordinated approach that moves the entire industry toward common health goals."

Meet the guest: Dr. Dustin Oedekoven / dusty-oedekoven-bb0bb7110 is Chief Veterinarian at the National Pork Board, where he leads initiatives to strengthen U.S. swine health through disease prevention, producer collaboration, and the National Swine Health Strategy. With more than 20 years of experience in veterinary public health and regulatory animal health, his work focuses on protecting the U.S. herd from endemic and foreign animal diseases. Listen to Dr. Dustin Oedekoven on The Swine it Podcast Show, available on all major platforms.