Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Oct 21, 2022

Coronaviruses use a broad range of host receptors for binding and cell entry, essential steps in establishing viral infections. This pilot study evaluated the overall distribution of angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and dipeptidyl peptidase 4 (DPP4) receptors in the pig respiratory and intestinal tract. All the receptors evaluated in this study were expressed and differentially distributed through the respiratory and intestinal tract. The presence and expression levels of these receptors could determine susceptibility to coronavirus infections. This study may have important implications for the development of research models and the assessment of the potential risk and introduction of novel coronaviruses into the swine population.

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Video: Hendrix Genetics Swine Raises the Bar: Delivering Robust Genetics for Pork Producers

The swine genetics landscape is evolving rapidly, and Hendrix Genetics Swine is leading the way. In this exclusive interview, Bryce Martin discusses how the integration of Hypor, Danish Genetics and the newly introduced Nexus product line is creating one of the industry's most comprehensive genetic portfolios. Producers across Canada, the United States and Europe are facing increasing pressure to improve efficiency, animal health, survivability and profitability, and Hendrix Genetics Swine is responding with genetics designed to meet those challenges.
Martin explains how the strengths of Hypor's balanced and sustainable breeding approach combine with Danish Genetics' reputation for robustness, growth performance and productivity to deliver solutions tailored to a wide range of production systems. The discussion also explores the launch of Nexus 100, a new sow developed from the combined expertise of both genetic programs and designed to improve predictability, survivability and total system profitability. For more information visit: https://swine.hendrix-genetics.com/en/