Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Oct 21, 2022

Coronaviruses use a broad range of host receptors for binding and cell entry, essential steps in establishing viral infections. This pilot study evaluated the overall distribution of angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and dipeptidyl peptidase 4 (DPP4) receptors in the pig respiratory and intestinal tract. All the receptors evaluated in this study were expressed and differentially distributed through the respiratory and intestinal tract. The presence and expression levels of these receptors could determine susceptibility to coronavirus infections. This study may have important implications for the development of research models and the assessment of the potential risk and introduction of novel coronaviruses into the swine population.

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Video: Sow Welfare and Group Housing Systems - Dr. Laya Alves

In this episode of The Swine it Podcast Show Canada, Dr. Laya Alves from the University of São Paulo, in Brazil, discusses how animal welfare regulations are evolving globally and their impact on pig production systems. She explains challenges in group housing, pain management, and euthanasia decisions, while highlighting the role of training and management in improving outcomes and economic sustainability. Listen now on all major platforms!

"Translating welfare requirements into daily farm routines without compromising economic sustainability remains one of the biggest challenges faced by producers globally today."

Meet the guest: Dr. Laya Alves / laya-kannan is a Postdoctoral Researcher at the University of São Paulo, Brazil, focusing on animal welfare in pig production, including pain management, euthanasia, and economic decision making. Her work integrates welfare science with practical farm management and sustainability. She collaborates globally to develop applied tools for producers.