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Feeding changes open opportunities

There’s a strong relationship between health and growth in a calf’s early life and that animal’s lifetime production. That means what happens to a calf in its first few hours and days is extremely critical, particularly concerning what it’s fed.

What, how much and when to feed calves is changing and opens new opportunities for producers to impact the long-term health, growth and productivity of their animals, said Michael Steele, a professor in the University of Guelph-Department of Animal Biosciences.

“You can mold the calf when it’s born,” he said. “We call this developmental plasticity, which is strong early in life and goes down as time goes on.”

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Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen

Video: Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen



In this episode of The Swine Nutrition Blackbelt Podcast, Dr. Li-Hsuan Chen, postdoc researcher at Aarhus University, discusses how porcine intestinal cell lines and organoids can help study the impact of nutrition on gut health. He explains how in vivo piglet trials identify diet-driven shifts in microbiota and metabolites, while in vitro models allow researchers to test specific metabolites, barrier function, immune markers, and future organ-on-chip systems before moving back to animal studies. Listen now on all major platforms!

"In vitro models can reduce early animal use by helping researchers screen nutritional candidates before moving back to in vivo trials."

Meet the guest: Dr. Li-Hsuan Chen / li-hsuan-chen-9a95a7279 is a postdoc researcher at Aarhus University in Denmark. Research focuses on porcine gut health, host-microbe interactions, cell lines, and organoids, with PhD work at Aarhus University studying how dietary protein and amino acid levels shape gut microbiota, microbial metabolites, and intestinal epithelial responses. Learn more from Dr. Li-Hsuan Chen on The Swine Nutrition Blackbelt Podcast, available on all major platforms.