Importance of the Pig as a Human Biomedical Model

Mar 01, 2022

Abstract: Importance of the pig as a human biomedical model - Science Translational Medicine

Pigs have substantial potential as biomedical models for studying human developmental processes, congenital diseases, and pathogen response mechanisms in addition to utility as xenotransplant organ donors and tools for vaccine and drug design. The similarity of pigs to humans in anatomical size and structure, physiology, immunology, and genome enhances their potential as models for humans. Hence, it is imperative that research is relevant and reproducible in animal models that more closely resemble humans, such as the pig. This review summarizes the current status of pigs as an investigative model for humans and highlights their future applications.

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Video: PRRS Eradication Strategies - Dr. DeBuse and Dr. Tousignant

In this episode of The Swine it Podcast Show, Dr. Neil DeBuse from Kalmbach Feeds and Dr. Steve Tousignant from Vaxxinova US discuss PRRS management strategies, recombination risks, whole genome sequencing, and the role of autogenous immunization programs in swine systems. They highlight practical approaches to improving immunity, reducing outbreaks, and advancing PRRS control across production systems. Listen now on all major platforms!

"Being PRRS negative sooner is a real key for eradication because every additional positive week increases production losses and viral exposure risks." - Dr. Neil DeBuse

Meet the guest: Dr. Neil DeBuse is a veterinarian at Kalmbach Feeds with more than 30 years of experience in swine health and production. His work focuses on PRRS control, biosecurity, immunity, and improving production stability across commercial swine systems in the United States and internationally.

Dr. Steve Tousignant is Director of the Swine Business Unit and Technical Services Veterinarian at Vaxxinova US, with a DVM and PhD from the University of Minnesota. His experience combines epidemiology, technical services, and practical immunization strategies designed to support consistent herd performance and long-term production stability. Don’t miss the chance to be part of the Swine Inner Circle!