Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Jun 24, 2022

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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Video: Causal Impact Of PRRS Dosing - Dr. Edison Magalhaes

In this episode of The Swine Health Blackbelt Podcast, Dr. Edison Magalhaes from Iowa State University presents findings from a large-scale retrospective cohort study evaluating the causal impact of full-dose PRRS immunization on nursery mortality. Using production data and advanced analytical methods, he explains how confounding factors changed the interpretation of results and highlights practical lessons for veterinarians and producers making data-driven decisions. Listen now on all major platforms!

Click here to read the full research article: https://pmc.ncbi.nlm.nih.gov/articles...

"Raw production data can mislead immunization decisions when confounding factors hide the real value of full-dose PRRS protocols."

Meet the guest: Dr. Edison Magalhaes / edison-magalhaes-9b37b812a is an Assistant Professor in the Department of Animal Science at Iowa State University and holds degrees in Veterinary Medicine, Business Administration, and advanced training through MSc and PhD programs. His research applies data science and epidemiological methods to large scale swine production systems, helping transform production records into practical decisions for health and performance. Listen to The Swine Health Blackbelt Podcast featuring Dr. Edison Magalhaes on all major platforms.