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Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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What It Takes to Stop African Swine Fever - Dr. Jishu Shi

Video: What It Takes to Stop African Swine Fever - Dr. Jishu Shi



In this episode of The Swine it Podcast Show Canada, Dr. Jishu Shi, Professor of Vaccine Immunology at Kansas State University, discusses African swine fever prevention and vaccine development. He explains why ASF differs from classical swine fever and swine influenza, how the disease threatens trade and pork production, why immunization safety remains a critical hurdle, and what producers can do now to reduce the risk of introduction. Listen now on all major platforms!

"Before a safe and efficacious vaccine for ASF can be commercialized, what we really have is prevention."

Meet the guest: Dr. Jishu Shi is Professor of Vaccine Immunology and the Dr. Wayne & Hilda Appleton Endowed Professor at Kansas State University’s College of Veterinary Medicine. He directs the Center on Biologics Development and Evaluation and the U.S.-China Center for Animal Health. A veterinarian and vaccine immunologist, Dr. Shi has focused on vaccines for pigs and has worked on African swine fever vaccine development, control, diagnostics, and international training since 2018. Learn more from Dr. Jishu Shi on The Swine it Podcast Show Canada, available on all major platforms.