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Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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Episode 82: Keep Your BVD Down

Video: Episode 82: Keep Your BVD Down

Bovine Viral Diarrhea (BVD) is a serious disease that can lead to abortion, infertility, immune suppression, and calf losses. If the virus crosses the placenta in the first four months of gestation, calves may be born persistently infected and shed high levels of the virus throughout their lives—posing a major risk to unvaccinated cattle. In this episode, we explore why it’s critical to keep BVD out of your herd and how different vaccination protocols can help protect your cattle.