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Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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Genetics vs Genomics in Swine - Dr. Max Rothschild

Video: Genetics vs Genomics in Swine - Dr. Max Rothschild



In this episode of The Swine it Podcast Show Canada, Dr. Max Rothschild, Distinguished Professor at Iowa State University, explains how genetics and genomics have transformed swine production. He explores genomic selection, key gene discoveries, and the role of gene editing in improving disease resistance and productivity. Practical insights on litter size, meat quality, and industry adoption are also discussed. Listen now on all major platforms!

"Genetic improvement in swine production accelerated significantly once molecular tools enabled identification of DNA level variation influencing growth, reproduction, and meat quality across commercial populations."

Meet the guest: Dr. Max Rothschild / max-f-rothschild-b3800312 earned his PhD in Animal Breeding from Cornell University and has spent over four decades at Iowa State University advancing swine genetics and genomics. His research focuses on genetic improvement, disease resistance, and molecular tools for swine production. A leader in pig genome research, his work has shaped modern breeding strategies.