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Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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ASF Control Lessons - Dr. Mary-Louise Penrith

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In this episode of The Swine it Podcast Show Canada, Dr. Mary-Louise Penrith, Extraordinary Professor at the University of Pretoria, shares what decades of work have revealed about ASF control. She explains why vaccine development remains difficult, how human activity and food waste drive disease spread, why resistant pig populations are an important research area, and how strict biosecurity with the right disinfectants can help to stop transmission. Listen now on all major platforms!

"It's really a very human-driven disease because people move pigs, decide how they're raised, how they're sold, and good biosecurity can do anything to ensure control."

Meet the guest: Dr. Mary-Louise Penrith / mary-louise-penrith-2b12bb42 is an Extraordinary Professor in the Department of Veterinary Tropical Diseases at the University of Pretoria, South Africa. A veterinarian and internationally recognized researcher, she has dedicated decades to African swine fever epidemiology, control, and pig health, supporting FAO and WOAH initiatives while advancing research and education. Listen to Dr. Mary-Louise Penrith on the Swine Health Blackbelt Podcast, available on all major platforms.