Phylogenetic Analysis of Porcine Circovirus 3 Circulating in Canadian Pigs

Jun 24, 2022

Abstract: Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs

Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.
Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.
Results: Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

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Video: Synthetic Microbiota Explained - Dr. Alexandre Thibodeau

In this episode of The Swine it Podcast Show Canada, Dr. Alexandre Thibodeau, from the University of Montreal, explains how synthetic microbiota and bioreactor systems can help researchers study gut microorganisms, evaluate feed additives, investigate Salmonella control strategies, and develop alternatives to animal trials. Listen now on all major platforms!

"Bioreactor models can screen microbiota solutions before animal trials, lowering costs and reducing the number of pigs needed."

Meet the guest: Dr. Alexandre Thibodeau / alexandre-thibodeau-2493a540 is an Associate Professor at the University of Montreal, in Canada, with a PhD in Veterinary Science and Microbiology. His work focuses on swine gut health, food safety, microbiota research, pathogen control, and alternative research models that support animal production and welfare. His research explores innovative strategies to better understand interactions among microorganisms and to improve livestock health outcomes. Learn more from Dr. Alexandre Thibodeau on The Swine it Podcast Show Canada, available on all major platforms.