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Working Safely with African Swine Fever Virus

Abstract: Working Safely with African Swine Fever Virus
Risk assessment is the cornerstone of working safely with biological agents.

The World Health Organization (WHO) Laboratory Biosafety Manual Fourth Edition Monograph on Risk Assessment provides stepwise guidance for carrying out a risk assessment, from gathering information and identifying hazards to evaluating the risks and developing and implementing controls and review. To support the development of a mature safety culture within laboratories, it is important that all staff who handle biological agents understand the process of risk assessment and receive training in identifying hazards and mitigating risk. All personnel can partake in risk assessments, and the guidance is written in such a way that it is applicable to all-not just to biosafety professionals, laboratory scientists, or facility managers. 

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Season 7, Episode 6: Using Competitive Exclusion to Reduce E. coli in Weaned Pigs

Video: Season 7, Episode 6: Using Competitive Exclusion to Reduce E. coli in Weaned Pigs

Newly weaned pigs are especially vulnerable to pathogenic E. coli, which can cause diarrhea and other health challenges. Research is exploring how introducing beneficial bacteria before exposure to harmful bacteria could help reduce the severity of post-weaning disease, with timing playing an important role.

Dr. Marcelo Almeida, assistant professor in Iowa State University’s College of Veterinary Medicine, and Dr. Rodrigo Paiva, graduate student and pathology resident at the Iowa State University Veterinary Diagnostic Laboratory, discuss their research on competitive exclusion in weaned pigs. They explain how this approach works, why introducing beneficial microorganisms before E. coli exposure may improve outcomes and what they learned about diarrhea, E. coli shedding and pig performance. The conversation also explores the potential to address antimicrobial resistance and the considerations for applying these findings in commercial pork production.